Have you been craving a midday candy pick-me-up or after-dinner dessert? You can blame that hankering on a simple fact: Sweet Tooth returns in April. And in Season 2, it’s time for the hybrids to fight back. 

The family-friendly fantasy series follows Gus (Christian Convery), a human-deer hybrid who was born at one of the most catastrophic times in history. Ten years before the series, a mysterious virus appeared, whipping out 98% of the globe’s population and throwing society into the Great Crumble, an era of debilitating chaos. As the Great Crumble destroyed the world as we knew it, something unexplainable also happened — the birth of human-animal hybrid babies like Gus. 

Are the hybrids the cause of the Great Crumble (and the cataclysmic virus known as the Sick)? Or are they the result of the virus? Warring factions have very different answers to these questions, putting Sweet Tooth’s heroes and villains on an unforgettable collision course. 

As teased in the Season 2 trailer above, Gus and his fellow hybrids will find new strength as they uncover the origins of the Great Crumble. Keep reading to find out  what you can expect to see in their next adventures, including new photos and cast details. 

When is Sweet Tooth’s release date? 

Sweet Tooth returns to tug on your heartstrings with Season 2 on April 27. It is executive produced by Robert Downey Jr., Susan Downey, Amanda Burrell and Linda Moran. 

What happens in Sweet Tooth?

In Sweet Tooth Season 2, a deadly new wave of the Sick is bearing down on humanity. Gus and a band of other child hybrids are held prisoner by the villainous General Abbot (Neil Sandilands) and the Last Men, a violent group of mercenaries who hunt hybrids. Abbot uses the children as fodder for the experiments of captive Dr. Aditya Singh (Adeel Akhtar); Abbot wants to find a cure and amass power, Dr. Singh simply wants to save his infected wife, Rani (Aliza Vellani). 

Gus, always a hero, agrees to help Dr. Singh, thus beginning a dark journey into discovering his own origins. He may also learn more about his mother, Birdie’s (Amy Seimetz) role in the events leading up to the Great Crumble. Elsewhere, Jepperd (Nonso Anozie) and Aimee Eden (Dania Ramirez ) team up to free the hybrids, creating a partnership that will be tested as Jepperd’s secrets come to light. 

Who is in the cast of Sweet Tooth? 

Convery leads Sweet Tooth Season 2 as Gus, the series’ naive and curious protagonist. Gus is a human-deer hybrid and the first of his kind. He sets out to explore the world following the death of his father, Richard, whom Gus called Pubba (Will Forte), and Gus finds a protector in former football player Jepperd, aka Big Man. Together, Gus and Tommy are each other’s chance at securing a newfound family at the end of the world. 

Here’s who else you’ll spot in Sweet Tooth Season 2: 

• Adeel Akhtar as Dr. Singh  
• Stefania LaVie Owen as Bear 
• Dania Ramirez as Aimee Eden 
• Aliza Vellani as Rani Singh
• Neil Sandilands as General Abbot
• Naledi Murray as Wendy
• Marlon Williams as Johnny Abbot
• Christopher Sean Cooper Jr. as Teddy 
• Yonas Kibreab as Finn 
• James Brolin as the voice of the narrator

Where are the Sweet Tooth photos? 

Get your first (and fantastical) look at Sweet Tooth Season 2 with these images. 

Can I watch the Sweet Tooth trailer? 

You sure can, above. The trailer takes us back into the Preserve, where the First Men have set up shop. Inside, the hybrid children realize the dangers afoot in their occupied home as Dr. Singh works to create a cure for the Sick. The watchful eye of villain and First Men leader General Abbot only adds to the terrifying tension.

But the trailer is also filled with hope, as we learn more about Birdie, the woman Gus originally believed was his mother. Whatever the truth is about Gus’ past, he’s ready to lead — and isn’t letting anyone get in his way.  

Is Sweet Tooth based on a comic book? 

Yes, it is. Sweet Tooth is inspired by the DC comic book series by Jeff Lemire, which debuted in 2009. While you’re welcome to dive into Lemire’s gorgeous comics, you don’t have to read the series to enjoy the twists and turns of Sweet Tooth Season 2.

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